Genome-Wide Analysis of the KLF Gene Family in Chicken: Characterization and Expression Profile.

ABSTRACT: The kruppel-like factor (KLF) gene family is a group of transcription factors containing highly conserved zinc-finger motifs, which play a crucial role in cell proliferation and differentiation. Chicken has been widely used as a model animal for analyzing gene function, however, little is known about the function of the KLF gene family in chickens. In this study, we performed genome-wide studies of chicken KLF genes and analyzed their biological and expression characteristics. We identified 13 KLF genes from chickens. Our phylogenetic, motif, and conserved domain analyses indicate that the KLF gene family has remained conserved through evolution. Synteny analysis showed the collinear relationship among KLFs, which indicated that they had related bi

SUBMITTER: Ling X 

PROVIDER: S-EPMC10177326 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature