The Role of MicroRNAs in Uterine Leiomyosarcoma Diagnosis and Treatment.

ABSTRACT: Uterine sarcomas are rare gynecological tumors arising from the myometrium or the connective tissue of the endometrium with a relatively poor prognosis. MicroRNAs (miRNAs) represent small, single-stranded, non-coding RNA molecules that can function as oncogenes or tumor suppressors under certain conditions. The current review aims at studying the role of miRNAs in uterine sarcoma diagnosis and treatment. In order to identify relevant studies, a literature review was conducted using the MEDLINE and LIVIVO databases. The search terms "microRNA" and "uterine sarcoma" were employed, and we were able to identify 24 studies published between 2008 and 2022. The current manuscript represents the first comprehensive review of the literature focusing on the particular role of miRNAs as biomarkers fo

SUBMITTER: Psilopatis I 

PROVIDER: S-EPMC10177388 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature