SNP-Based Heritability of Osteochondrosis Dissecans in Hanoverian Warmblood Horses.

ABSTRACT: Before the genomics era, heritability estimates were performed using pedigree data. Data collection for pedigree analysis is time consuming and holds the risk of incorrect or incomplete data. With the availability of SNP-based arrays, heritability can now be estimated based on genotyping data. We used SNP array and 1.6 million imputed genotype data with different minor allele frequency restrictions to estimate heritabilities for osteochondrosis dissecans in the fetlock, hock and stifle joints of 446 Hanoverian warmblood horses. SNP-based heritabilities were estimated using a genomic restricted maximum likelihood (GREML) method and accounting for patterns of regional linkage disequilibrium in the equine genome. In addition, we employed GREML for family data to account for different degrees

SUBMITTER: Zimmermann E 

PROVIDER: S-EPMC10177438 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature