Basal Ganglia Compensatory White Matter Changes on DTI in Alzheimer's Disease.

ABSTRACT: The volume reduction of the gray matter structures in patients with Alzheimer's disease is often accompanied by an asymmetric increase in the number of white matter fibers located close to these structures. The present study aims to investigate the white matter structure changes in the motor basal ganglia in Alzheimer's disease patients compared to healthy controls using diffusion tensor imaging. The amounts of tracts, tract length, tract volume, quantitative anisotropy, and general fractional anisotropy were measured in ten patients with Alzheimer's disease and ten healthy controls. A significant decrease in the number of tracts and general fractional anisotropy was found in patients with Alzheimer's disease compared to controls in the right caudate nucleus, while an increase was found in

SUBMITTER: Wurst Z 

PROVIDER: S-EPMC10177535 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature