Effects of Silirum^®-Based Vaccination Programs on Map Fecal Shedding and Serological Response in Seven French Dairy Herds.

ABSTRACT: (1) Background: paratuberculosis is an important disease in ruminants, causing worldwide economic losses to the livestock industry. Although vaccination is known not to prevent transmission of the causative agent Mycobacterium avium subsp. paratuberculosis (Map), it is considered an effective tool for paratuberculosis in infected herds. The objectives of this controlled field study were to evaluate the effects of the whole-cell heat-killed Silirum^® vaccine on Map fecal shedding and serological status in dairy herds infected with paratuberculosis. (2) Methods: The serological status (ELISA) and fecal shedding (qPCR) of 358 vaccinated cows were assessed over 3 years in 7 infected dairy herds in the Meuse department, France. Within each herd, cows from the last non-va

SUBMITTER: Corbiere F 

PROVIDER: S-EPMC10177616 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature