Therapeutic Lymphangiogenesis Is a Promising Strategy for Secondary Lymphedema.

ABSTRACT: Secondary lymphedema is caused by lymphatic insufficiency (lymphatic drainage failure) following lymph node dissection during the surgical treatment or radiation therapy of breast or pelvic cancer. The clinical problems associated with lymphedema are reduced quality of life in terms of appearance and function, as well as the development of skin ulcers, recurrent pain, and infection. Currently, countermeasures against lymphedema are mainly physical therapy such as lymphatic massage, elastic stockings, and skin care, and there is no effective and fundamental treatment with a highly recommended grade. Therefore, there is a need for the development of a fundamental novel treatment for intractable lymphedema. Therapeutic lymphangiogenesis, which has been attracting attention in recent years, is

SUBMITTER: Shimizu Y 

PROVIDER: S-EPMC10178056 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature