Influence of Leptin on the Secretion of Growth Hormone in Ewes under Different Photoperiodic Conditions.

ABSTRACT: Leptin is an adipokine with a pleiotropic impact on many physiological processes, including hypothalamic-pituitary-somatotropic (HPS) axis activity, which plays a key role in regulating mammalian metabolism. Leptin insensitivity/resistance is a pathological condition in humans, but in seasonal animals, it is a physiological adaptation. Therefore, these animals represent a promising model for studying this phenomenon. This study aimed to determine the influence of leptin on the activity of the HPS axis. Two in vivo experiments performed during short- and long-day photoperiods were conducted on 12 ewes per experiment, and the ewes were divided randomly into 2 groups. The arcuate nucleus, paraventricular nucleus, anterior pituitary (AP) tissues, and blood were collected. The concentration of

SUBMITTER: Wojcik M 

PROVIDER: S-EPMC10178528 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature