Lipoprotein(a) As a Risk Factor in a Cohort of Hospitalised Cardiovascular Patients: A Retrospective Clinical Routine Data Analysis.

ABSTRACT:

Introduction

Lipoprotein(a) (Lp(a)) is a well-recognised risk factor for ischemic heart disease (IHD) and calcific aortic valve stenosis (AVS).

Methods

A retrospective observational study of Lp(a) levels (mg/dL) in patients hospitalised for cardiovascular diseases (CVD) in our clinical routine was performed. The Lp(a)-associated risk of hospitalisation for IHD, AVS, and concomitant IHD/AVS versus other non-ischemic CVDs (oCVD group) was assessed by means of logistic regression.

Results

In total of 11,767 adult patients, the association with Lp(a) was strongest in the IHD/AVS group (e^β = 1.010, p < 0.001), followed by the IHD (e^β = 1.008, p < 0.001) and AVS group (e^β = 1.004, p < 0.001). With increasing Lp(a) levels

SUBMITTER: Suran D 

PROVIDER: S-EPMC10178911 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature