Ontology highlight
ABSTRACT:
SUBMITTER: Ismail TF
PROVIDER: S-EPMC10179093 | biostudies-literature | 2023 Apr
REPOSITORIES: biostudies-literature

Journal of clinical medicine 20230425 9
Hypertensive heart disease (HHD) develops in response to the chronic exposure of the left ventricle and left atrium to elevated systemic blood pressure. Left ventricular structural changes include hypertrophy and interstitial fibrosis that in turn lead to functional changes including diastolic dysfunction and impaired left atrial and LV mechanical function. Ultimately, these changes can lead to heart failure with a preserved (HFpEF) or reduced (HFrEF) ejection fraction. This review will outline ...[more]