A New Microarchitecture-Based Parameter to Predict the Micromechanical Properties of Bone Allografts.

ABSTRACT: Scaffolds are an essential component of bone tissue engineering. They provide support and create a physiological environment for cells to proliferate and differentiate. Bone allografts extracted from human donors are promising scaffolds due to their mechanical and structural characteristics. Bone microarchitecture is well known to be an important determinant of macroscopic mechanical properties, but its role at the microscopic, i.e., the trabeculae level is still poorly understood. The present study investigated linear correlations between microarchitectural parameters obtained from X-ray computed tomography (micro-CT) images of bone allografts, such as bone volume fraction (BV/TV), degree of anisotropy (DA), or ellipsoid factor (EF), and micromechanical parameters derived from micro-finit

SUBMITTER: Xiong Z 

PROVIDER: S-EPMC10179528 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature