Supramolecular β-Cyclodextrin-Quercetin Based Metal-Organic Frameworks as an Efficient Antibiofilm and Antifungal Agent.

ABSTRACT: The loading of drugs or medicinally active compounds has recently been performed using metal-organic frameworks (MOFs), which are thought to be a new type of porous material in which organic ligands and metal ions can self-assemble to form a network structure. The quercetin (QRC) loading and biofilm application on a cyclodextrin-based metal-organic framework via a solvent diffusion approach is successfully accomplished in the current study. The antibacterial plant flavonoid QRC is loaded onto β-CD-K MOFs to create the composite containing inclusion complexes (ICs) and denoted as QRC:β-CD-K MOFs. The shifting in the chemical shift values of QRC in the MOFs may be the reason for the interaction of QRC with the β-CD-K MOFs. The binding energies and relative contents of MOFs are considerably c

SUBMITTER: Rajamohan R 

PROVIDER: S-EPMC10179912 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature