Prenatal Vitamin D Levels Influence Growth and Body Composition until 11 Years in Boys.

ABSTRACT:

Background

Gestational vitamin D levels may influence offspring growth and modulate adipogenesis. Findings from prospective studies are inconsistent, and few have evaluated the persistence of these associations into late childhood.

Objective

To examine the association between prenatal vitamin D levels and growth and adiposity in late childhood.

Methods

We included 2027 mother-child pairs from the INMA birth cohort. 25-hydroxyvitamin D₃ (vitamin D₃) levels were measured in serum at 13 weeks of pregnancy. Sex- and age-specific body mass index z-scores were calculated at 7 and 11 years, overweight was defined as z-score ≥ 85th percentile, and body fat mass was measured at 11 years. Z-score body mass index (zBMI) trajectories from birth to 11 years w

SUBMITTER: Sanguesa J 

PROVIDER: S-EPMC10181475 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature