Executive functioning in preschoolers with 22q11.2 deletion syndrome and the impact of congenital heart defects.

ABSTRACT:

Background

Executive functioning (EF) is an umbrella term for various cognitive functions that play a role in monitoring and planning to effectuate goal-directed behavior. The 22q11.2 deletion syndrome (22q11DS), the most common microdeletion syndrome, is associated with a multitude of both somatic and cognitive symptoms, including EF impairments in school-age and adolescence. However, results vary across different EF domains and studies with preschool children are scarce. As EF is critically associated with later psychopathology and adaptive functioning, our first aim was to study EF in preschool children with 22q11DS. Our second aim was to explore the effect of a congenital heart defects (CHD) on EF abilities, as CHD are common in 22q11DS and have been implicated in EF impairment

SUBMITTER: Everaert E 

PROVIDER: S-EPMC10181926 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature