Risk of autoimmune skin and connective tissue disorders after mRNA-based COVID-19 vaccination.

ABSTRACT:

Background

Data on the association between the development of autoimmune diseases and COVID-19 vaccination are limited.

Objective

To investigate the incidence and risk of autoimmune connective tissue disorders following mRNA-based COVID-19 vaccination.

Methods

This nationwide population-based study was conducted in South Korea. Individuals who received vaccination between September 8, 2020-December 31, 2021, were identified. Historical prepandemic controls were matched for age and sex in 1:1 ratio. The incidence rate and risk of disease outcomes were compared.

Results

A total of 3,838,120 vaccinated individuals and 3,834,804 controls without evidence of COVID-19 were included. The risk of alopecia areata, alopecia totalis, primary cicatricial alopecia, psoriasi

SUBMITTER: Ju HJ 

PROVIDER: S-EPMC10182598 | biostudies-literature | 2023 Oct

REPOSITORIES: biostudies-literature