Resection of pancreatic neuroendocrine tumors: defining patterns and time course of recurrence.

ABSTRACT:

Background

To define recurrence patterns and time course, as well as risk factors associated with recurrence following curative resection of pNETs.

Method

Patients who underwent curative-intent resection for pNET between 1997 and 2016 were identified from the US Neuroendocrine Tumor Study Group. Data on baseline and tumor-specific characteristics, overall survival (OS), timing and first-site of recurrence, predictors and recurrence management were analyzed.

Results

Among 1020 patients, 154 (15.1%) patients developed recurrence. Among patients who experienced recurrence, 76 (49.4%) had liver-only recurrence, while 35 (22.7%) had pancreas-only recurrence. The proportion of liver-only recurrence increased from 54.3% within one-year after surgery to 61.5% from four-to-six

SUBMITTER: Dong DH 

PROVIDER: S-EPMC10182895 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature