A bioinformatics analysis of the susceptibility genes in Stanford type A aortic dissection.

ABSTRACT:

Background

The expression levels of long noncoding RNAs (lncRNAs) and mRNAs in human acute Stanford type A aortic dissecting aneurysm and normal active vascular tissues were compared using the array lncRNA/mRNA expression profile chip technology.

Methods

The tissue samples of 5 patients who presented with Stanford type A aortic dissections and the normal ascending aorta tissues from 5 donor heart transplantation patients receiving surgical treatment in Ganzhou People's Hospital were collected. Hematoxylin and eosin (HE) staining were performed to investigate the structural features of the ascending aortic vascular tissue. Nanodropnd-100 was used to detect the surface level of RNA in 10 samples included in the experiment, to ensure that the quality of the standard was consist

SUBMITTER: Peng X 

PROVIDER: S-EPMC10183510 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature