Improved diagnostic yield of symptom association probability involving only cough for gastroesophageal reflux-induced chronic cough.

ABSTRACT:

Background

Use of symptom association probability (SAP) is recommended for identifying gastroesophageal reflux-induced chronic cough (GERC). This study aimed to compare the diagnostic yield of SAPs involving only cough (C-SAP) or total symptoms (T-SAP) for GERC identification.

Methods

Patients with both chronic cough and other reflux-related symptoms underwent multichannel intraluminal impedance-pH monitoring (MII-pH) between January 2017 and May 2021. C-SAP and T-SAP were calculated based on the patient-reported symptoms. GERC was definitively diagnosed by the favorable response to anti-reflux therapy. The diagnostic yield of C-SAP in identifying GERC was evaluated by receiver operating characteristic curve analysis and compared with that of T-SAP.

Results

MII-pH was

SUBMITTER: Zhang L 

PROVIDER: S-EPMC10183512 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature