A pan-cancer analysis of ABI3BP: a potential biomarker for prognosis and immunoinfiltration.

ABSTRACT:

Objective

ABI Family Member 3 Binding Protein (ABI3BP) is an extracellular matrix protein that affects the carcinogenesis of lung and esophageal cancer. However, the relevance of ABI3BP in different forms of cancer is uncertain.

Methods

ABI3BP expression was interpreted using the Cancer Genome Atlas (TCGA) database, the Genotype Tissue Expression Atlas (GTEx) database, the Human Protein Atlas (HPA) database, the Cancer Cell Line Encyclopedia (CCLE) database, and immunohistochemistry. The R programming language was used to analyze the association between ABI3BP expression and patient prognosis and evaluate the relationship between ABI3BP and the immune characteristics of tumors. Using the GDSC and CTRP databases, a drug sensitivity analysis of ABI3BP was conducted.

Results

SUBMITTER: Feng Y 

PROVIDER: S-EPMC10183607 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature