Post-dural puncture headache prevention and treatment with aminophylline or theophylline: a systematic review and meta-analysis.

ABSTRACT:

Background

Post-dural puncture headache (PDPH) is one of the most common complications in patients undergoing spinal anesthesia. The present systematic review and meta-analysis aimed to assess the therapeutic and prophylactic effects of aminophylline and theophylline on PDPH.

Methods

Relevant studies were identified by searching the following electronic databases, without language restriction, until June 2020: Scopus, EMBASE, MEDLINE, Google Scholar, Web of Science, Cochrane Library-CENTRAL, and CINAHL Complete. Random effects models were used to calculate the standardized mean difference (SMD) and risk ratios (RRs) with 95% confidence intervals (95% CI) to assess the therapeutic and prophylactic effects of aminophylline and theophylline on PDPH, respectively. The Cochrane t

SUBMITTER: Barati-Boldaji R 

PROVIDER: S-EPMC10183611 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature