Effect of CannEpil^® on simulated driving performance and co-monitoring of ocular activity: A randomised controlled trial.

ABSTRACT:

Background

Medicinal cannabis products containing Δ9-tetrahydrocannabinol (THC) are increasingly accessible. Yet, policy guidelines regarding fitness to drive are lacking, and cannabinoid-specific indexations of impairment are underdeveloped.

Aims

To determine the impact of a standardised 1 mL sublingual dose of CannEpil^®, a medicinal cannabis oil containing 100 mg cannabidiol (CBD) and 5 mg THC on simulated driving performance, relative to placebo and whether variations in vehicle control can be indexed by ocular activity.

Methods

A double-blind, within-subjects, randomised, placebo-controlled, crossover trial assessed 31 healthy fully licensed drivers (15 male, 16 female) aged between 21 and 58 years (M = 38.0, SD = 10.78). Standard deviation of la

SUBMITTER: Manning B 

PROVIDER: S-EPMC10184186 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature