FVC/D_LCO identifies pulmonary hypertension and predicts 5-year all-cause mortality in patients with COPD.

ABSTRACT:

Background

Pulmonary hypertension (PH) is a common complication of chronic obstructive pulmonary disease (COPD). However, it is unknown whether the ratio of forced vital capacity (FVC) to diffusing lung capacity for carbon monoxide (D_LCO) can identify PH in the patients with COPD and predict its prognosis.

Methods

The study population I included 937 COPD patients who were admitted to inpatient treatments from 2010 to 2017, and finally 750 patients were available to follow-up the 5-year all-cause mortality (study population II). Clinical characteristics of the study population were recorded.

Results

COPD patients with PH had a higher FVC/D_LCO value compared with the patients without PH. The threshold for FVC/D_LCO to identify PH in COPD

SUBMITTER: Li Y 

PROVIDER: S-EPMC10184375 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature