Urinary aluminium and its association with autism spectrum disorder in urban preschool children in Malaysia.

ABSTRACT:

Background

The presence of aluminium (Al) in the human body may impact brain neurodevelopment and function, and it is thought to contribute to autism spectrum disease (ASD). The main objective of this study was to assess the association between urinary Al and the development of ASD among Malaysian preschool children in the urban city of Kuala Lumpur.

Method

This was an unmatched case-control study in which children with ASD were recruited from an autism early intervention center and typically developed (TD) children were recruited from government-run nurseries and preschools. Urine samples were collected at home, assembled temporarily at study locations, and transported to the laboratory within 24 h. The Al concentration in the children's urine samples was determined using i

SUBMITTER: Abd Wahil MS 

PROVIDER: S-EPMC10184655 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature