Sentinel lymph node mapping in patients with endometrial hyperplasia: A practice to preserve or abandon?

ABSTRACT:

Objectives

To compare outcomes of patients with premalignant endometrial pathology undergoing hysterectomy with or without sentinel lymph node (SLN) removal. Outcomes of interest included surgical adverse events (AEs), cancer status on final pathology, postoperative treatment, and The Cancer Genome Atlas (TCGA) molecular risk profiles.

Methods

We retrospectively identified patients with premalignant pathology on preoperative endometrial biopsy who underwent hysterectomy with or without SLN mapping/excision at our institution from 01/01/2017-12/31/2021. Clinical, pathologic, surgical, and TCGA profiling data were abstracted. Appropriate statistical tests were used.

Results

Of 221 patients identified, 161 (73%) underwent hysterectomy with SLN excision and 60 (27%) under

SUBMITTER: Mueller JJ 

PROVIDER: S-EPMC10184678 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature