Ontology highlight
ABSTRACT:
SUBMITTER: Yabuuchi H
PROVIDER: S-EPMC10184910 | biostudies-literature | 2023
REPOSITORIES: biostudies-literature
Yabuuchi Hiroaki H Hayashi Kazuhito K Shigemoto Akihiko A Fujiwara Makiko M Nomura Yuhei Y Nakashima Mayumi M Ogusu Takeshi T Mori Megumi M Tokumoto Shin-Ichi SI Miyai Kazuyuki K
PloS one 20230515 5
Plant extract is a mixture of diverse phytochemicals, and considered as an important resource for drug discovery. However, large-scale exploration of the bioactive extracts has been hindered by various obstacles until now. In this research, we have introduced and evaluated a new computational screening strategy that classifies bioactive compounds and plants in semantic space generated by word embedding algorithm. The classifier showed good performance in binary (presence/absence of bioactivity) ...[more]