Imbalance of Microbacterial Diversity Is Associated with Functional Prognosis of Stroke.

ABSTRACT:

Objectives

There is mounting evidence to suggest that the pathophysiology of stroke is greatly influenced by the microbiota of the gut and its metabolites, in particular short-chain fatty acids (SCFAs). The primary purpose of the study was to evaluate whether the levels of SCFAs and the gut microbiota are altered in poststroke patients and to examine the relationship between these alterations and the physical condition, intestinal health, pain, or nutritional status of patients.

Methods

Twenty stroke patients and twenty healthy controls were enrolled in the current study, and their demographics were matched. Gas chromatography was used to determine the fecal SCFAs, and 16S rRNA gene sequencing was used to evaluate their fecal microbiota. Microbial diversity and richness were

SUBMITTER: Zhang X 

PROVIDER: S-EPMC10185427 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature