Influence of the modifiers in polyol method on magnetically induced hyperthermia and biocompatibility of ultrafine magnetite nanoparticles.

ABSTRACT: Magnetite nanoparticles (Fe₃O₄ NPs) are widely tested in various biomedical applications, including magnetically induced hyperthermia. In this study, the influence of the modifiers, i.e., urotropine, polyethylene glycol, and NH₄HCO_3, on the size, morphology, magnetically induced hyperthermia effect, and biocompatibility were tested for Fe₃O₄ NPs synthesized by polyol method. The nanoparticles were characterized by a spherical shape and similar size of around 10 nm. At the same time, their surface is functionalized by triethylene glycol or polyethylene glycol, depending on the modifiers. The Fe₃O₄ NPs synthesized in the presence of urotropine had the highest colloidal stability related to the high positi

SUBMITTER: Radon A 

PROVIDER: S-EPMC10185678 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature