Growth of late preterm infants fed nutrient-enriched formula to 120 days corrected age-A randomized controlled trial.

ABSTRACT:

Objectives

We aimed to compare the effects of nutrient-enriched formula with standard term formula on rate of body weight gain of late preterm infants appropriately grown for gestational age.

Study design

A multi-center, randomized, controlled trial. Late preterm infants (34-37 weeks' gestation), with weight appropriate for gestational age (AGA), were randomized to nutrient enriched formula (NEF) with increased calories (22 kcal/30 ml) from protein, added bovine milk fat globule membrane, vitamin D and butyrate or standard term formula 20 kcal/30 ml (STF). Breastfed term infants were enrolled as an observational reference group (BFR). Primary outcome was rate of body weight gain from enrollment to 120 days corrected age (d/CA). Planned sample size was 100 infants per group.

SUBMITTER: Best KP 

PROVIDER: S-EPMC10185835 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature