Dataset Information

Effect of multicomponent interventions on tuberculosis notification in mining and pastoralist districts of Oromia region in Ethiopia: a longitudinal quasi-experimental study.

ABSTRACT:

Objective

To demonstrate the impact of interventions on tuberculosis (TB) case detection in mining and pastoralist districts in southeastern Ethiopia over a 10-year period.

Design

Longitudinal quasi-experimental study.

Setting

Health centres and hospitals in six mining districts implemented interventions and seven nearby districts functioned as controls.

Participants

Data from the national District Health Information System (DHIS-2) were used for this study; therefore, people did not participate in this study.

Interventions

Directed at training, active case finding and improving treatment outcomes.

Primary and secondary outcome measures

Primarily, trends in TB case notification and percentage of bacteriologically confirmed TB-as collected by DHIS-2-between pre-intervention (2012-2015) and post-intervention (2016-2021) were analysed. Secondarily, post-intervention was split into early post-intervention (2016-2018) and late post-intervention (2019-2021) to also study the long-term effects of the intervention.

Results

For all forms of TB, case notification significantly increased between pre-intervention and early post-intervention (incidence rate ratio (IRR): 1.21, 95% CI: 1.13, 1.31; p<0.001) and significantly decreased between pre-intervention/early post-intervention and late post-intervention (IRR: 0.82, 95% CI: 0.76, 0.89; p<0.001 and IRR: 0.67, 95% CI: 0.62, 0.73; p<0.001). For bacteriologically confirmed cases, we found a significant decrease between pre-intervention/early post-intervention and late post-intervention (IRR: 0.88, 95% CI: 0.81, 0.97; p<0.001 and IRR: 0.81, 95% CI: 0.74, 0.89; p<0.001). The percentage of bacteriologically confirmed cases was significantly lower in the intervention districts during pre-intervention (B: -14.24 percentage points, 95% CI: -19.27, -9.21) and early post-intervention (B: -7.78, 95% CI: -15.46, -0.010; p=0.047). From early post-intervention to late post-intervention, we found a significant increase (B: 9.12, 95% CI: 0.92 to 17.33; p=0.032).

Conclusions

The decrease in TB notifications in intervention districts during late post-intervention is possibly due to a decline in actual TB burden as a result of the interventions. The unabated increase in case notification in control districts may be due to continued TB transmission in the community.

SUBMITTER: de Groot LM

PROVIDER: S-EPMC10186083 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature

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Publications

Effect of multicomponent interventions on tuberculosis notification in mining and pastoralist districts of Oromia region in Ethiopia: a longitudinal quasi-experimental study.

de Groot Liza Marlette LM Dememew Zewdu Gashu ZG Hiruy Nebiyu N Datiko Daniel Gemechu DG Gebreyes Solomon Negash SN Suarez Pedro G PG Jerene Degu D

BMJ open 20230515 5

<h4>Objective</h4>To demonstrate the impact of interventions on tuberculosis (TB) case detection in mining and pastoralist districts in southeastern Ethiopia over a 10-year period.<h4>Design</h4>Longitudinal quasi-experimental study.<h4>Setting</h4>Health centres and hospitals in six mining districts implemented interventions and seven nearby districts functioned as controls.<h4>Participants</h4>Data from the national District Health Information System (DHIS-2) were used for this study; therefor ...[more]

PMID: 37188473

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Dataset Information

Effect of multicomponent interventions on tuberculosis notification in mining and pastoralist districts of Oromia region in Ethiopia: a longitudinal quasi-experimental study.

Objective

Design

Setting

Participants

Interventions

Primary and secondary outcome measures

Results

Conclusions

Publications

Effect of multicomponent interventions on tuberculosis notification in mining and pastoralist districts of Oromia region in Ethiopia: a longitudinal quasi-experimental study.

Similar Datasets

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