Covalent organic framework-MnO₂ nanoparticle composites for shape-selective sensing of bithiols.

ABSTRACT: Covalent organic frameworks (COFs) for detecting biological macromolecules in water or biological environments are generally challenging. In this work, a composite material IEP-MnO₂ is obtained by combining manganese dioxide (MnO₂) nanocrystals and a fluorescent COF (IEP), which is synthesized by using 2,4,6-tris(4-aminophenyl)-s-triazine and 2,5-dimethoxyterephthalaldehyde. By the addition of biothiols, such as glutathione, cysteine or homocysteine with different sizes, the fluorescence emission spectra of IEP-MnO₂ changed ("turn-on" or "turn-off") via different mechanisms. The fluorescence emission of IEP-MnO₂ increased in the presence of GSH by the elimination of the FRET (Förster resonance energy transfer) effect between MnO

SUBMITTER: Cao Y 

PROVIDER: S-EPMC10186332 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature