Role of epithelial cell-mesenchymal transition regulators in molecular typing and prognosis of colon cancer.

ABSTRACT:

Background

Despite advances in colon cancer screening, diagnosis, chemotherapy, and targeted therapy, the prognosis remains poor once colon cancer develops distant metastasis or local recurrence. To further improve the prognosis of colon cancer patients, researchers or clinicians may need to identify new indicators for predicting the prognosis and treatment of colon cancer.

Methods

In order to discover the new mechanism of epithelial-mesenchymal transition (EMT) promoting tumor progression and to find new indicators of colon cancer diagnosis, targeted therapy and prognosis, this study conducted The Cancer Genome Atlas (TCGA) analysis, differential gene analysis, prognostic analysis, protein-protein interaction (PPI), enrichment analysis, molecular typing, and a machine algor

SUBMITTER: He S 

PROVIDER: S-EPMC10186519 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature