Primary tumor location impacts survival in colorectal cancer patients after primary resection: a population‑based propensity score matching cohort study.

ABSTRACT:

Background

Right-sided colon cancers (R-CCs) are associated with worse outcomes compared to left-sided colon cancers (L-CCs). This study aimed to investigate whether a difference in survival existed among R-CC, L-CC, and rectal cancer (ReC) and subsequent liver metastasis.

Methods

Data from the Surveillance, Epidemiology, and End Results (SEER) database for 2010-2015 was used to identify colorectal cancer (CRC) patients who underwent surgical resection of primary disease. Propensity score adjustment and Cox regression models were used to identify risk factors and prognostic factors of primary tumor location (PTL). Kaplan-Meier curve analysis and the log-rank test were used to evaluate overall survival (OS) of CRC patients.

Results

Our results showed that among the 73,

SUBMITTER: Yin H 

PROVIDER: S-EPMC10186525 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature