Progressive resolution optimizer (PRO) predominates over photon optimizer (PO) in sparing of spinal cord for spine SABR VMAT plans.

ABSTRACT:

Background

we assessed the performance of the optimization algorithms by comparing volumetric modulated arc therapy generated by a progressive resolution optimized (VMAT_PRO) and photon optimizer (VMAT_PO) in terms of plan quality, MU reduction, sparing of the spinal cord (or cauda equina), and plan complexity.

Methods

Fifty-seven patients who received spine stereotactic ablative radiotherapy (SABR) with tumors located in the cervical, thoracic, and lumbar spine were retrospectively selected. For each patient, VMAT_PRO and VMAT_PO with two full arcs were generated with using the PRO and PO algorithms. For dosimetric evaluation, the dose-volumetric (DV) parameters of the planning target volume (PTV), organs at risk (OARs), the correspon

SUBMITTER: Son S 

PROVIDER: S-EPMC10186649 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature