Predictors for post-treatment biopsy outcomes after prostate stereotactic body radiotherapy.

ABSTRACT:

Purpose

To investigate predictors associated with post-treatment biopsy outcomes after stereotactic body radiotherapy (SBRT) for localized prostate cancer.

Materials and methods

257 patients treated with prostate SBRT to dose levels of 32.5 Gy to >40 Gy in 5-6 fractions underwent a post-treatment biopsy performed approximately two years after treatment to evaluate local control status. 73 had% intermediate-risk disease (n = 187) and the remaining 17% (n = 43) and 10% (n = 27) had low-risk and high-risk disease, respectively.

Results

The incidence of positive, negative, and treatment-effect post-treatment biopsies were 15.6%, 57.6%, and 26.8%, respectively. The incidence of a positive biopsy according to dose was 37.5% (n = 9/24), 21.4% (n = 6/28), 19.4% (n = 6/31), an

SUBMITTER: Zelefsky MJ 

PROVIDER: S-EPMC10187562 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature