Elective neck dissection versus observation in patients with head and neck cutaneous squamous cell carcinoma.

ABSTRACT:

Background

The survival benefit of elective neck dissection (END) for patients with cutaneous squamous cell carcinoma (cSCC) of the head and neck and no evidence of regional metastasis (cN0) has never been reported. The aim of this study was to determine the effect of END on patient survival.

Methods

The authors included patients with head and neck cSCC who had undergone primary surgery from 1995 to 2017. The primary end point was survival, and the secondary end points were the incidence of occult regional disease and regional disease control. To assess the impact of END on survival, the authors used multivariable Cox proportional hazards models with propensity score and matching techniques for internal validation.

Results

A total of 1111 patients presented with no ev

SUBMITTER: Amit M 

PROVIDER: S-EPMC10187975 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature