Metabolic response to radiation therapy in cancer.
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ABSTRACT:
SUBMITTER: Read GH
PROVIDER: S-EPMC10187995 | biostudies-literature | 2022 Feb
REPOSITORIES: biostudies-literature
Publications
Metabolic response to radiation therapy in cancer.
Read Graham H GH Bailleul Justine J Vlashi Erina E Kesarwala Aparna H AH
Molecular carcinogenesis 20211227 2
Tumor metabolism has emerged as a hallmark of cancer and is involved in carcinogenesis and tumor growth. Reprogramming of tumor metabolism is necessary for cancer cells to sustain high proliferation rates and enhanced demands for nutrients. Recent studies suggest that metabolic plasticity in cancer cells can decrease the efficacy of anticancer therapies by enhancing antioxidant defenses and DNA repair mechanisms. Studying radiation-induced metabolic changes will lead to a better understanding of ...[more]
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