Association of survival with adjuvant radiotherapy for pN0 esophageal cancer.

ABSTRACT:

Introduction

This study was conducted to elucidate the link between adjuvant radiotherapy and survival in pathologic node-negative (pN0) esophageal cancer patients with upfront esophagectomy.

Methods

From 2000 to 2016, patients with pN0 esophageal cancer who underwent upfront esophagectomy were selected from the Surveillance, Epidemiology, and End Results (SEER) database. The association of high-risk covariates with survival after adjuvant radiotherapy was evaluated using propensity score matching and multivariate analysis.

Results

We identified 3197 patients, 321 (10.0%) underwent postoperative radiotherapy and 2876 (90.0%) underwent esophagectomy alone. In the unmatched cohort, postoperative radiotherapy was associated with a statistically significant but modest abs

SUBMITTER: Gao H 

PROVIDER: S-EPMC10188340 | biostudies-literature | 2023 Apr

REPOSITORIES: biostudies-literature