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Assessment of current clinical practice throughout the UK for the diagnosis and management of monoclonal gammopathy of renal significance.


ABSTRACT: Since the inception of the term monoclonal gammopathy of renal significance (MGRS) in 2012 by the International Kidney and Monoclonal Gammopathy Research Group, there have been no consensus guidelines specifically pertaining to the UK regarding to patient management. We aimed to identify both regional and cross-discipline variation in current clinical practice, to provide insight and rationale for a potential standardised pathway in the future. A national survey of 88 consultants from the disciplines of haematology and nephrology was conducted between June 2020 and July 2021. Agreement was evident for aspects of the diagnostic pathway, including presenting features likely to raise suspicion of MGRS and the most pertinent confounding factors to consider before renal biopsy. However, signifi

SUBMITTER: Choudhuri S 

PROVIDER: S-EPMC10188446 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature