The prognostic value of multiparametric cardiac magnetic resonance in patients with systemic light chain amyloidosis.

ABSTRACT:

Background

Late gadolinium enhancement (LGE) is a classic imaging modality derived from cardiac magnetic resonance (CMR), which is commonly used to describe cardiac tissue characterization. T1 mapping with extracellular volume (ECV) and native T1 are novel quantitative parameters. The prognostic value of multiparametric CMR in patients with light chain (AL) amyloidosis remains to be thoroughly investigated.

Methods

A total of 89 subjects with AL amyloidosis were enrolled from April 2016 to January 2021, and all of them underwent CMR on a 3.0 T scanner. The clinical outcome and therapeutic effect were observed. Cox regression was used to investigate the effect of multiple CMR parameters on outcomes in this population.

Results

LGE extent, native T1 and ECV correlated we

SUBMITTER: Miao F 

PROVIDER: S-EPMC10189062 | biostudies-literature | 2023

REPOSITORIES: biostudies-literature