Migraine with aura: less control over pain and fragrances?

ABSTRACT:

Background

Accumulating data emphasizes the importance of olfaction in migraine pathophysiology. However, there are only a few studies evaluating how the migraine brain processes olfactory stimulation, and virtually no studies comparing patients with and without aura in this context.

Methods

This cross-sectional study recorded event-related potentials from 64 electrodes during a pure olfactory or pure trigeminal stimulus in females with episodic migraine with aura (n = 13) and without aura (n = 15), to characterize the central nervous processing of these intranasal stimuli. Patients were tested in interictal state only. Data were analyzed in the time domain and in the time-frequency domain. Source reconstruction analysis was also performed.

Results

Patients with aura

SUBMITTER: Mignot C 

PROVIDER: S-EPMC10189721 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature