Dysregulated endothelial cell markers in systemic lupus erythematosus: a systematic review and meta-analysis.

ABSTRACT:

Objectives

To perform a systematic literature review and meta-analysis on endothelial cell (EC) markers that are involved and dysregulated in systemic lupus erythematosus (SLE) in relation to disease activity, as EC dysregulation plays a major role in the development of premature atherosclerosis in SLE.

Methods

Search terms were entered into Embase, MEDLINE, Web of Science, Google Scholar and Cochrane. Inclusion criteria were 1) studies published after 2000 reporting measurements of EC markers in serum and/or plasma of SLE patients (diagnosed according to ACR/SLICC criteria), 2) English language peer reviewed articles, and 3) disease activity measurement. For meta-analysis calculations, the Meta-Essentials tool by Erasmus Research Institute and of Management (ERIM) was used.

SUBMITTER: Bergkamp SC 

PROVIDER: S-EPMC10189957 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature