Connectome-based prediction of craving in gambling disorder and cocaine use disorder.

ABSTRACT:

Introduction

Craving, involving intense and urgent desires to engage in specific behaviours, is a feature of addictions. Multiple studies implicate regions of salience/limbic networks and basal ganglia, fronto-parietal, medial frontal regions in craving in addictions. However, prior studies have not identified common neural networks that reliably predict craving across substance and behavioural addictions.

Methods

Functional magnetic resonance imaging during an audiovisual cue-reactivity task and connectome-based predictive modelling (CPM), a data-driven method for generating brain-behavioural models, were used to study individuals with cocaine-use disorder and gambling disorder. Functions of nodes and networks relevant to craving were identified and interpreted based on met

SUBMITTER: Antons S 

PROVIDER: S-EPMC10190201 | biostudies-literature | 2023 Dec

REPOSITORIES: biostudies-literature