Advanced Temporally-Spatially Precise Technologies for On-Demand Neurological Disorder Intervention.

ABSTRACT: Temporal-spatial precision has attracted increasing attention for the clinical intervention of neurological disorders (NDs) to mitigate adverse effects of traditional treatments and achieve point-of-care medicine. Inspiring steps forward in this field have been witnessed in recent years, giving the credit to multi-discipline efforts from neurobiology, bioengineering, chemical materials, artificial intelligence, and so on, exhibiting valuable clinical translation potential. In this review, the latest progress in advanced temporally-spatially precise clinical intervention is highlighted, including localized parenchyma drug delivery, precise neuromodulation, as well as biological signal detection to trigger closed-loop control. Their clinical potential in both central and peripheral nervous s

SUBMITTER: Chen X 

PROVIDER: S-EPMC10190591 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature