An efficient 3D stack-of-stars turbo spin echo pulse sequence for simultaneous T2-weighted imaging and T2 mapping.

ABSTRACT:

Purpose

To design a pulse sequence for efficient 3D T2-weighted imaging and T2 mapping.

Methods

A stack-of-stars turbo spin echo pulse sequence with variable refocusing flip angles and a flexible pseudorandom view ordering is proposed for simultaneous T2-weighted imaging and T2 mapping. An analytical framework is introduced for the selection of refocusing flip angles to maximize relative tissue contrast while minimizing T2 estimation errors and maintaining low specific absorption rate. Images at different echo times are generated using a subspace constrained iterative reconstruction algorithm. T2 maps are obtained by modeling the signal evolution using the extended phase graph model. The technique is evaluated using phantoms and demonstrated in vivo for brain, knee, and caro

SUBMITTER: Keerthivasan MB 

PROVIDER: S-EPMC10191119 | biostudies-literature | 2019 Jul

REPOSITORIES: biostudies-literature