A novel insight on SARS-CoV-2 S-derived fragments in the control of the host immunity.

ABSTRACT: Despite all efforts to combat the pandemic of COVID-19, we are still living with high numbers of infected persons, an overburdened health care system, and the lack of an effective and definitive treatment. Understanding the pathophysiology of the disease is crucial for the development of new technologies and therapies for the best clinical management of patients. Since the manipulation of the whole virus requires a structure with an adequate level of biosafety, the development of alternative technologies, such as the synthesis of peptides from viral proteins, is a possible solution to circumvent this problem. In addition, the use and validation of animal models is of extreme importance to screen new drugs and to compress the organism's response to the disease. Peptides derived from recombi

SUBMITTER: Bastos TSB 

PROVIDER: S-EPMC10191404 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature