Association of the time of day of peak physical activity with cardiovascular mortality: Findings from the UK Biobank study.

ABSTRACT: Cardiovascular physiology and pathophysiology display pronounced circadian rhythms. The study is designed to examine whether the time of day of physical activity is associated with cardiovascular mortality. We analyzed 94,489 UK Biobank adults with objectively measured physical activity, including 53,328 morning-type participants and 30,962 evening-type participants based on self-reported chronotypes. The time of day of peak physical activity was categorized using a machine learning algorithm: early morning (n = 18,477), late morning (n = 25,700), midday (reference) (n = 27,803), and night (n = 22,509). Hazard ratios of cardiovascular mortality were examined using the Cox proportional hazards model. During a median follow-up of 6.9 years (interquartile range, 6.3-7.4 years), we identified

SUBMITTER: Ma T 

PROVIDER: S-EPMC10192159 | biostudies-literature | 2023 Mar

REPOSITORIES: biostudies-literature