Effect of cetrimonium carrier micelles on bacterial membranes and extracellular DNA, an in silico study.

ABSTRACT: Microorganisms do not live as dispersed single cells but rather they form aggregates with extracellular polymeric substances at interfaces. Biofilms are considered efficient life forms because they shield bacteria from biocides and collect dilute nutrients. This is a big concern in industry since the microorganisms can colonize a wide range of surfaces, accelerating material deterioration, colonizing medical devices, contaminating ultrapure drinking water, increasing energy costs and creating focus of infection. Conventional biocides that target a specific component of the bacteria are not effective in the presence of biofilms. Efficient biofilm inhibitors are based on a multitarget approach interacting with the bacteria and the biofilm matrix. Their rationale design requires a thorough un

SUBMITTER: Puelles JS 

PROVIDER: S-EPMC10192197 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature