Responses of pyramidal cell somata and apical dendrites in mouse visual cortex over multiple days.

ABSTRACT: The apical dendrites of pyramidal neurons in sensory cortex receive primarily top-down signals from associative and motor regions, while cell bodies and nearby dendrites are heavily targeted by locally recurrent or bottom-up inputs from the sensory periphery. Based on these differences, a number of theories in computational neuroscience postulate a unique role for apical dendrites in learning. However, due to technical challenges in data collection, little data is available for comparing the responses of apical dendrites to cell bodies over multiple days. Here we present a dataset collected through the Allen Institute Mindscope's OpenScope program that addresses this need. This dataset comprises high-quality two-photon calcium imaging from the apical dendrites and the cell bodies of visual

SUBMITTER: Gillon CJ 

PROVIDER: S-EPMC10192216 | biostudies-literature | 2023 May

REPOSITORIES: biostudies-literature