Effects of angiotensin receptor-neprilysin inhibitor on insulin resistance in patients with heart failure.

ABSTRACT:

Aims

Although the haemodynamic effects of angiotensin receptor-neprilysin inhibitor (ARNI) on patients with heart failure have been demonstrated, the effect on glucose metabolism has not been fully elucidated. We retrospectively investigated the effect of ARNI on abnormal glucose metabolism in patients with stable chronic heart failure using an additional structural equation model (SEM) analysis.

Methods

We analysed 34 patients who regularly visited to the outpatient department of our institute with heart failure from October 2021 and July 2022 and who were taking angiotensin-converting enzyme (ACE) inhibitors or angiotensin receptor blockers (ARBs). Seventeen patients switched from ACE inhibitors or ARBs to an ARNI (ARNI group), and the other 17 patients continued treatment

SUBMITTER: Kashiwagi Y 

PROVIDER: S-EPMC10192229 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature