Association between changes in loop diuretic dose and outcomes in acute heart failure.

ABSTRACT:

Aims

Little is known about the association between the starting of or dose changes in loop diuretics during acute heart failure (AHF) hospitalization and post-discharge outcomes. We investigated the clinical impact of starting loop diuretics and changing the loop diuretics dose during hospitalization on post-discharge outcomes.

Methods and results

From the Kyoto Congestive Heart Failure registry, 3665 consecutive patients hospitalized for HF and discharged alive were included in this study. We analysed 1906 patients without loop diuretics on admission and were discharged alive and 1759 patients who received loop diuretics on admission and were discharged alive. The primary outcome measure was all-cause death. Of the 1906 patients without loop diuretics on admission, 1366 (71

SUBMITTER: Seko Y 

PROVIDER: S-EPMC10192247 | biostudies-literature | 2023 Jun

REPOSITORIES: biostudies-literature