Challenges and future scope of exosomes in the treatment of cardiovascular diseases.

ABSTRACT: Exosomes are nanosized vesicles that carry biologically diverse molecules for intercellular communication. Researchers have been trying to engineer exosomes for therapeutic purposes by using different approaches to deliver biologically active molecules to the various target cells efficiently. Recent technological advances may allow the biodistribution and pharmacokinetics of exosomes to be modified to meet scientific needs with respect to specific diseases. However, it is essential to determine an exosome's optimal dosage and potential side effects before its clinical use. Significant breakthroughs have been made in recent decades concerning exosome labelling and imaging techniques. These tools provide in situ monitoring of exosome biodistribution and pharmacokinetics and pinpoint targetab

SUBMITTER: Ranjan P 

PROVIDER: S-EPMC10192497 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature